After graduation in law, she got her diploma in direction at the CSC. She is a director and a screenwriter. Her debut with “L’isola” at the Quinzaine des Réalisateurs, 56th Cannes Film Festival in 2003 earned her important awards, such as the Cicae Prize and the Fipresci. In the same year the making of “Racconti per l'isola” was invited to the Venice Film Festival. With 'Terramatta' in 2013 and 'Triangle' in 2015 Costanza Quatriglio was therefore twice awarded with the Nastro d’Argento for best documentary. Among her awarded documentaries presented to the major International Festivals (Venice Film Festival, Locarno Festival, Turin, Madrid, Rome): 'Ècosaimale'? (2000), 'Il bambino Gioacchino' (2000), 'La borsa di Hélène' (2000), 'L'insonnia di Devi' (2001), 'Raìz' (2004) 'Il mondo addosso' (2006), 'Il mio cuore umano' (2009), 'Terramatta' (2012), 'Con il fiato sospeso' (2013), 'Triangle' (2014), '87 hours' (2015). In 2018 she  is back to the Locarno Festival with the film 'Sembra mio figlio', awarded with the Ciak d’Oro, and in the same year she received the Visioni dal Mondo award. Costanza Quatriglio also worked for tv. In 2007 was the creative producer of the italian tv series 'Un posto al sole'. She has been teaching film directing, documentary cinema and dramaturgy of reality for over 15 years: one of the early founders of the Gian Maria Volonté Film School, lecturer at the Master in Ideation and Film Production for Università Cattolica, IED (European Institute of Design), Master in Cinema of the Real for the Università Roma Tre, for the Holden School and for the Rome and Palermo CSC, both in Rome and in Palermo. From 2019 she is the Art Director and Teaching Coordinator of the documentary course.